Management of Humeral Shaft Fractures With Intramedullary Interlocking Nail Versus Locking Compression Plate
Abstract
Surgical fixation of humeral shaft fractures generally involves plating or nailing. It is unclear whether one method is more effective than the other. The aim of this study was to compare the results of the intramedullary nail and locking compression plate for the treatment of humeral shaft fractures. A total of 60 patients with humeral shaft fractures were randomized to undergo surgery with an intramedullary interlocking nail (n=30) or locking compression plate (n=30). The outcome was assessed in terms of intraoperative blood loss, operative time, hospital stay, union time, union rate, functional outcome, and incidence of complications. Functional outcome was assessed using the Constant score and the American Shoulder and Elbow Surgeons (ASES) score. Intraoperative blood loss, operative time, and hospital stay in group A (intramedullary interlocking nail) were significantly lower than those in group B (locking compression plate). No statistically significant difference was found regarding the union rate, mean Constant score, and mean ASES score between the groups. The average union time was found to be significantly lower for the intramedullary interlocking nail compared with the locking compression plate. The incidence of complications such as radial nerve palsy was found to be higher with the locking compression plate compared with the intramedullary interlocking nail. The intramedullary interlocking nail can be considered a better surgical option for the management of humeral shaft fractures because it offers decreased intraoperative blood loss; shorter operative times, hospital stays, and union times; and a lower incidence of serious complications such as radial nerve palsy. [Orthopedics. 2015; 38(9):e825–e829.]
- 1.Singisetti K, Ambedkar M. Nailing versus plating in humerus shaft fractures: a prospective comparative study. Int Orthop. 2010; 34(4):571–576.
10.1007/s00264-009-0813-2 Crossref Medline, Google Scholar - 2.Rose SH, Melton LJ, Morrey BF, Ilstrup DM, Riggs BL. Epidemiologic features of humeral fractures. Clin Orthop Relat Res. 1982; 168:24–30. Crossref, Google Scholar
- 3.Tsai CH, Fong YC, Chen YH, Hsu CJ, Chang CH, Hsu HC. The epidemiology of traumatic humeral shaft fractures in Taiwan. Int Orthop. 2009; 33(2):463–467.
10.1007/s00264-008-0537-8 Crossref Medline, Google Scholar - 4.Ghosh S, Halder TC, Chaudhuri A, Datta S, Dasgupta S, Mitra UK. Comparative study of operative treatment of mid shaft fracture of humerus by locking plate versus intramedullary interlocking nail. Medical Journal of Dr DY Patil University. 2013; 6(4):390–394.
10.4103/0975-2870.118282 Crossref, Google Scholar - 5.Li Y, Wang C, Wang M, Huang L, Huang Q. Postoperative malrotation of humeral shaft fracture after plating compared with intramedullary nailing. J Shoulder Elbow Surg. 2011; 20(6):947–954.
10.1016/j.jse.2010.12.016 Crossref Medline, Google Scholar - 6.Ring D, Jupiter JB. Internal fixation of the humerus with locking compression plates. Tech Shoulder Elbow Surg. 2003; 4(4):169–174.
10.1097/00132589-200312000-00003 Crossref, Google Scholar - 7.Naveen PR, Chaitanya PR. Comparative study between the dynamic compression plating (DCP) and the intramedullary interlocking nailing in diaphyseal fractures of the humerus in adults. Journal of Evolution of Medical and Dental Sciences. 2013; 2(45):8704–8712.
10.14260/jemds/1511 Crossref, Google Scholar - 8.Changulani M, Jain UK, Keswani T. Comparison of the use of the humerus intramedullary nail and dynamic compression plate for the management of diaphyseal fractures of the humerus: a randomised controlled study. Int Orthop. 2007; 31(3):391–395.
10.1007/s00264-006-0200-1 Crossref Medline, Google Scholar - 9.Rommens PM, Kuechle R, Bord T, Lewens T, Engelmann R, Blum J. Humeral nailing revisited. Injury. 2008; 39(12):1319–1328.
10.1016/j.injury.2008.01.014 Crossref Medline, Google Scholar - 10.Ajmal M, O’Sullivan M, McCabe J, Curtin W. Antegrade locked intramedullary nailing in humeral shaft fractures. Injury. 2001; 32(9):692–694.
10.1016/S0020-1383(01)00076-6 Crossref Medline, Google Scholar - 11.Flinkkilä T, Ristiniemi J, Hämäläinen M. Nonunion after intramedullary nailing of humeral shaft fractures. J Trauma. 2001; 50(3):540–544.
10.1097/00005373-200103000-00021 Crossref Medline, Google Scholar - 12.Liu GD, Zhang QG, Ou S, Meta-analysis of the outcomes of intramedullary nailing and plate fixation of humeral shaft fractures. Int J Surg. 2013; 11(9):864–868.
10.1016/j.ijsu.2013.08.002 Crossref Medline, Google Scholar - 13.Kurup H, Hossain M, Andrew JG. Dynamic compression plating versus locked intramedullary nailing for humeral shaft fractures in adults. Cochrane Database Syst Rev. 2011; 6:CD005959. Medline, Google Scholar
- 14.McCormack RG, Brien D, Buckley RE, McKee MD, Powell J, Schemitsch EH. Fixation of fractures of the shaft of the humerus by dynamic compression plate or intramedullary nail: a prospective, randomised trial. J Bone Joint Surg Br. 2000; 82(3):336–339.
10.1302/0301-620X.82B3.9675 Crossref Medline, Google Scholar - 15.Kumar R, Singh P, Chaudhary LJ, Singh S. Humeral shaft fracture management: a prospective study; nailing or plating. J Clin Orthop Trauma. 2012; 3(1):37–42.
10.1016/j.jcot.2012.04.003 Crossref Medline, Google Scholar - 16.Dai J, Chai Y, Wang C, Wen G. Dynamic compression plating versus locked intramedullary nailing for humeral shaft fractures: a meta-analysis of RCTs and nonrandomized studies. J Orthop Sci. 2014; 19(2):282–291.
10.1007/s00776-013-0497-8 Crossref Medline, Google Scholar - 17.Putti AB, Uppin RB, Putti BB. Locked intramedullary nailing versus dynamic compression plating for humeral shaft fractures. J Orthop Surg (Hong Kong). 2009; 17(2):139–141. Crossref Medline, Google Scholar
- 18.Ouyang H, Xiong J, Xiang P, Cui Z, Chen L, Yu B. Plate versus intramedullary nail fixation in the treatment of humeral shaft fractures: an updated meta-analysis. J Shoulder Elbow Surg. 2013; 22(3):387–395.
10.1016/j.jse.2012.06.007 Crossref Medline, Google Scholar - 19.Jiang R, Luo CF, Zeng BF, Mei GH. Minimally invasive plating for complex humeral shaft fractures. Arch Orthop Trauma Surg. 2007; 127(7):531–535.
10.1007/s00402-007-0313-z Crossref Medline, Google Scholar - 20.Wagner M. General principles for the clinical use of the LCP. Injury. 2003; 34(suppl 2):B31–B42.
10.1016/j.injury.2003.09.023 Crossref Medline, Google Scholar - 21.Seide K, Morlock MM, Schuemann U, Wolter D. Mechanical effects of the locked screw plate interface in internal fixator osteosynthesis. Trauma Berufskrankh. 1999; 1:320–325.
10.1007/s100390050056 Crossref, Google Scholar - 22.Puri SR, Biswas SK, Salgia A, Sanghi S, Aggarwal T, Kohli A. Operative management of fracture of shaft humerus by dynamic compression plate versus interlocking intramedullary nailing: a comparative prospective study of 30 cases. Medical Journal of Dr DY Patil University. 2013; 6(1):49–54.
10.4103/0975-2870.108641 Crossref, Google Scholar - 23.Bhandari M, Devereaux PJ, Mckee MD, Schemitsch EH. Compression plating versus intramedullary nailing of humeral shaft fractures: a meta-analysis. Acta Orthop. 2006; 77(2):279–284.
10.1080/17453670610046037 Crossref Medline, Google Scholar - 24.Chapman JR, Henley MB, Agel J, Benca PJ. Randomized prospective study of humeral shaft fracture fixation: intramedullary nails versus plates. J Orthop Trauma. 2000; 14(3):162–166.
10.1097/00005131-200003000-00002 Crossref Medline, Google Scholar - 25.Rodríguez-Merchán EC. Compression plating versus hackethal nailing in closed humeral shaft fractures failing nonoperative reduction. J Orthop Trauma. 1995; 9(3):194–197.
10.1097/00005131-199506000-00003 Crossref Medline, Google Scholar - 26.Raghavendra S, Bhalodiya HP. Internal fixation of fractures of the shaft of the humerus by dynamic compression plate or intramedullary nail: a prospective study. Indian J Orthop. 2007; 41(3):214–218.
10.4103/0019-5413.33685 Crossref Medline, Google Scholar - 27.Bell MJ, Beauchamp CG, Kellam JK, McMurtry RY. The results of plating humeral shaft fractures in patients with multiple injuries: the Sunnybrook experience. J Bone Joint Surg Br. 1985; 67(2):293–296. Crossref Medline, Google Scholar
- 28.Dabezies EJ, Banta CJ, Murphy CP, D’Ambrosia RD. Plate fixation of the humeral shaft for acute fractures, with and without radial nerve injuries. J Orthop Trauma. 1992; 6(1):10–13. Medline, Google Scholar
- 29.Heim D, Herkert F, Hess P, Regazzoni P. Surgical treatment of humeral shaft fractures: the Basel experience. J Trauma. 1993; 35(2):226–232.
10.1097/00005373-199308000-00009 Crossref Medline, Google Scholar - 30.Pollock FH, Drake D, Bovill EG, Day L, Trafton PG. Treatment of radial neuropathy associated with fractures of the humerus. J Bone Joint Surg Am. 1981; 63(2):239–243. Crossref Medline, Google Scholar
- 31.Hems TE, Bhullar TP. Interlocking nailing of humeral shaft fractures: the Oxford experience, 1991–1994. Injury. 1996; 27(7):485–489.
10.1016/0020-1383(96)00056-3 Crossref Medline, Google Scholar - 32.An Z, Zeng B, He X, Chen Q, Hu S. Plating osteosynthesis of mid-distal humeral shaft fractures: minimally invasive versus conventional open reduction technique. Int Orthop. 2010; 34(1):131–135.
10.1007/s00264-009-0753-x Crossref Medline, Google Scholar - 33.Garcia A, Maeck BH. Radial nerve injuries in fractures of the shaft of the humerus. Am J Surg. 1960; 99:625–627.
10.1016/0002-9610(60)90003-9 Crossref Medline, Google Scholar - 34.Kettelkamp DB, Alexander H. Clinical review of radial nerve injury. J Trauma. 1967; 7(3):424–432.
10.1097/00005373-196705000-00007 Crossref Medline, Google Scholar - 35.Crates J, Whittle AP. Antegrade interlocking nailing of acute humeral shaft fractures. Clin Orthop Relat Res. 1998; 350:40–50.
10.1097/00003086-199805000-00005 Crossref, Google Scholar

