Skip to main content
Published Online:https://doi.org/10.3928/01477447-20161017-02Cited by:6

Abstract

Expandable endoprostheses have become an acceptable modality to address the issue of limb-length inequality in limb-sparing procedures for skeletally immature patients afflicted with lower extremity bone sarcomas. This study retrospectively analyzed postoperative outcomes and complications for 7 patients (8 limbs) who underwent minimally invasive or noninvasive reconstruction during a 12-year period. Musculoskeletal Tumor Society (MSTS) scores and complication rates were reported. Mean functional outcome (MSTS scores) at final follow-up was 93.3%. Functional outcomes for the noninvasive and minimally invasive expandable prostheses were 97% and 85%, respectively. Complications included temporary peroneal nerve palsy (2 limbs), infection (2 limbs), prosthesis revision (3 limbs), stiffness (3 limbs), and wound healing problems (3 limbs). None of the patients required amputation. Both minimally and noninvasive expandable prostheses appear to be safe and reliable means of reconstruction that permit limb salvage in skeletally immature patients and provide good functional results considering the alternative is above-knee amputation or hip disarticulation. Although complications are frequent (range, 13%–38%), they often can be managed successfully without amputation, thus providing a good quality of life and functional limb. The noninvasive prosthesis may prove to be a more attractive option by potentially negating additional surgeries and reducing infection rates; however, the short-term experience with this prosthesis warrants further investigations with more patients and longer follow-up. [Orthopedics. 2017; 40(1):e157–e163.]

  • 1.Jeys L, Abudu A, Grimer R. Expandable prostheses. In: , Malawer MM, Wittig JC, Bickels J, eds. Operative Techniques in Orthopaedic Surgical Oncology. Philadelphia, PA: Lippincott Williams & Wilkins; 2012:46–54.

    Google Scholar
  • 2.Neel MD, Letson GD. Modular endoprostheses for children with malignant bone tumors. Cancer Control. 2001; 8(4):344–348.

    Crossref MedlineGoogle Scholar
  • 3.Dotan A, Dadia S, Bickels J, et al.Expandable endoprosthesis for limb-sparing surgery in children: long-term results. J Child Orthop. 2010; 4(5):391–400.10.1007/s11832-010-0270-x

    Crossref MedlineGoogle Scholar
  • 4.Simon MA, Aschliman MA, Thomas N, Mankin HJ. Limb-salvage treatment versus amputation for osteosarcoma of the distal end of the femur. J Bone Joint Surg Am. 1986; 68(9):1331–1337.

    Crossref MedlineGoogle Scholar
  • 5.Lewis MM, Pafford J, Spires W. The expandable prosthesis: tumor prosthesis in children. In: , Coombs R, Friedlaender G, eds. Bone Tumour Management. London, United Kingdom: Butterworths; 1987:177–183.

    Google Scholar
  • 6.Hwang JS, Mehta AD, Yoon RS, Beebe KS. From amputation to limb salvage reconstruction: evolution and role of the endoprosthesis in musculoskeletal oncology. J Orthop Traumatol. 2014; 15(2):81–86.10.1007/s10195-013-0265-8

    Crossref MedlineGoogle Scholar
  • 7.Lewis MM, Bloom N, Esquieres EM, Kenan S, Ryniker DM. The expandable prosthesis: an alternative to amputation for children with malignant bone tumors. AORN J. 1987; 46(3):457–470.10.1016/S0001-2092(07)66457-6

    Crossref MedlineGoogle Scholar
  • 8.Wilkins RM, Soubeiran A. The Phenix expandable prosthesis: early American experience. Clin Orthop Relat Res. 2001; 382:51–58.10.1097/00003086-200101000-00009

    CrossrefGoogle Scholar
  • 9.Neel MD, Wilkins RM, Rao BN, Kelly CM. Early multicenter experience with a noninvasive expandable prosthesis. Clin Orthop Relat Res. 2003; 415:72–81.10.1097/01.blo.0000093899.12372.25

    CrossrefGoogle Scholar
  • 10.Saghieh S, Abboud MR, Muwakkit SA, Saab R, Rao B, Haidar R. Seven-year experience of using Repiphysis expandable prosthesis in children with bone tumors. Pediatr Blood Cancer. 2010; 55(3):457–463.10.1002/pbc.22598

    Crossref MedlineGoogle Scholar
  • 11.Gupta A, Meswania J, Pollock R, et al.Noninvasive distal femoral expandable endoprosthesis for limb-salvage surgery in paediatric tumours. J Bone Joint Surg Br. 2006; 88(5):649–654.10.1302/0301-620X.88B5.17098

    Crossref MedlineGoogle Scholar
  • 12.Picardo NE, Blunn GW, Shekkeris AS, et al.The medium-term results of the Stanmore non-invasive extendible endoprosthesis in the treatment of paediatric bone tumours. J Bone Joint Surg Br. 2012; 94(3):425–430.10.1302/0301-620X.94B3.27738

    Crossref MedlineGoogle Scholar
  • 13.Anderson M, Green WT, Messner MB. Growth and predictions of growth in the lower extremities. J Bone Joint Surg Am. 1963; 45:1–14.

    Crossref MedlineGoogle Scholar
  • 14.Paley D, Bhave A, Herzenberg JE, Bowen JR. Multiplier method for predicting limb-length discrepancy. J Bone Joint Surg Am. 2000; 82(10):1432–1446.

    Crossref MedlineGoogle Scholar
  • 15.Enneking WF, Dunham W, Gebhardt MC, Malawar M, Pritchard DJ. A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system. Clin Orthop Relat Res. 1993; 286:241–246.

    CrossrefGoogle Scholar
  • 16.Ness KK, Neel MD, Kaste SC, et al.A comparison of function after limb salvage with non-invasive expandable or modular prostheses in children. Eur J Cancer. 2014; 50(18):3212–3220.10.1016/j.ejca.2014.10.005

    Crossref MedlineGoogle Scholar
  • 17.Ruggieri P, Mavrogenis AF, Pala E, Romantini M, Manfrini M, Mercuri M. Outcome of expandable prostheses in children. J Pediatr Orthop. 2013; 33(3):244–253.10.1097/BPO.0b013e318286c178

    Crossref MedlineGoogle Scholar
  • 18.Dominkus M, Krepler P, Schwameis E, Windhager R, Kotz R. Growth prediction in extendable tumor prostheses in children. Clin Orthop Relat Res. 2001; 390:212–220.10.1097/00003086-200109000-00024

    CrossrefGoogle Scholar
  • 19.Eckardt JJ, Kabo JM, Kelley CM, et al.Expandable endoprosthesis reconstruction in skeletally immature patients with tumors. Clin Orthop Relat Res. 2000; 373:51–61.10.1097/00003086-200004000-00008

    CrossrefGoogle Scholar
  • 20.Grimer RJ, Belthur M, Carter SR, Tillman RM, Cool P. Extendible replacements of the proximal tibia for bone tumours. J Bone Joint Surg Br. 2000; 82(2):255–260.10.1302/0301-620X.82B2 .9863

    Crossref MedlineGoogle Scholar
  • 21.Schiller C, Windhager R, Fellinger EJ, Salzer-Kuntschik M, Kaider A, Kotz R. Extendable tumour endoprostheses for the leg in children. J Bone Joint Surg Br. 1995; 77(4):608–614.

    Crossref MedlineGoogle Scholar
  • 22.Schindler OS, Cannon SR, Briggs TW, Blunn GW. Stanmore custom-made extendible distal femoral replacements: clinical experience in children with primary malignant bone tumours. J Bone Joint Surg Br. 1997; 79(6):927–937.10.1302/0301-620X.79B6.7164

    Crossref MedlineGoogle Scholar
  • 23.Henderson ER, Groundland JS, Pala E, et al.Failure mode classification for tumor endoprostheses: retrospective review of five institutions and a literature review. J Bone Joint Surg Am. 2011; 93(5):418–429.10.2106/JBJS.J.00834

    Crossref MedlineGoogle Scholar
  • 24.Beebe K, Song KJ, Ross E, Tuy B, Patterson F, Benevenia J. Functional outcomes after limb-salvage surgery and endoprosthetic reconstruction with an expandable prosthesis: a report of 4 cases. Arch Phys Med Rehabil. 2009; 90(6):1039–1047.10.1016/j.apmr.2008.12.025

    Crossref MedlineGoogle Scholar
  • 25.Cipriano CA, Gruzinova IS, Frank RM, Gitelis S, Virkus WW. Frequent complications and severe bone loss associated with the Repiphysis expandable distal femoral prosthesis. Clin Orthop Relat Res. 2015; 473(3):831–838.10.1007/s11999-014-3564-3

    Crossref MedlineGoogle Scholar

We use cookies on this site to enhance your user experience. For a complete overview of all the cookies used, please see our privacy policy.

×