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Imaging Clinical Science

Anterior Segment Optical Coherence Tomography as a Screening Tool for the Assessment of the Anterior Segment Angle

    Published Online: by:29


    <div class="ftSection"><span class="ftInlineSubsectionTitle">Background and Objective:</span><p>Anterior segment optical coherence tomography (AS-OCT) is an alternative method for the assessment of angle width. The purpose of this study is to assess the accuracy of AS-OCT for detecting occludable angles and compare the results of high- and low-resolution images with gonioscopy.</p></div><div class="ftSection"><span class="ftInlineSubsectionTitle">Patients and Methods:</span><p>Visante AS-OCT (Carl Zeiss Meditec, Dublin, CA) images of 303 eyes (155 patients) presenting between February 1 and July 15, 2007, were retrospectively analyzed. Angle recess area (ARA) and angle opening distances (AOD) at 250, 500, and 750 μm were measured and correlated with the corresponding gonioscopic measurements.</p></div><div class="ftSection"><span class="ftInlineSubsectionTitle">Results:</span><p>AS-OCT parameters showed a nonlinear relationship with gonioscopy, ARA having the highest correlation. Correlations between high- and low-resolution images were modest. Cut-off values were 0.180 mm<sup>2</sup> (70.3% sensitivity, 87.4% specificity) for ARA and 0.264 mm (71.8% sensitivity, 84.8% specificity) for AOD at 500 μm.</p></div><div class="ftSection"><span class="ftInlineSubsectionTitle">Conclusion:</span><p>AS-OCT appears to be a promising screening tool for narrow angles.</p></div>

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