Spectral-Domain Optical Coherence Tomography of the Choroid in Choroidal Osteoma
Abstract
The authors report spectral-domain optical coherence tomography (SD-OCT) findings in a patient with decalcifying choroidal osteoma accompanied by a choroidal neovascular membrane and serous retinal detachment. A 13-year-old girl was found to have a choroidal osteoma in the left eye. The clinical diagnosis was confirmed by B-scan ultrasonography, computed tomography, and fluorescein and indocyanine green angiography. The SD-OCT findings over the decalcified portion included serous retinal detachment, photoreceptor outer segment disorganization, retinal pigment epithelial atrophy, deformed Bruch’s membrane, and choroidal neovascular membrane. In contrast, the retinal structures over the calcified portion appeared to be preserved. SD-OCT showed loss of a vascular appearance and increased thickness in the affected choroid, especially in the decalcified portion. Choroidal thickening may be associated not only with choroidal osteomas, but also with tumor decalcification. These unique features on SD-OCT may be important in understanding poor visual prognosis when decalcification involves the fovea.
- 1.Shields CL, Shields JA, Augsburger JJ. Choroidal osteoma. Surv Ophthalmol. 1988; 33:17–27.
10.1016/0039-6257(88)90069-0 Crossref Medline, Google Scholar - 2.Gass JD, Guerry RK, Jack RL, Harris G. Choroidal Osteoma. Arch Ophthalmol. 1978; 96:428–435.
10.1001/archopht.1978.03910050204002 Crossref Medline, Google Scholar - 3.Shields CL, Perez B, Materin MA, Mehta S, Shields JA. Optical coherence tomography of choroidal osteoma in 22 cases: evidence for photoreceptor atrophy over the decalcified portion of the tumor. Ophthalmology. 2007; 114:e53–e58.
10.1016/j.ophtha.2007.07.037 Crossref Medline, Google Scholar - 4.Aylward GW, Chang TS, Pautler SE, Gass JD. A long-term follow-up of choroidal osteoma. Arch Ophthalmol. 1998; 116:1337–1341. Crossref Medline, Google Scholar
- 5.Shields CL, Sun H, Demirci H, Shields JA. Factors predictive of tumor growth, tumor decalcification, choroidal neovascularization, and visual outcome in 74 eyes with choroidal osteoma. Arch Ophthalmol. 2005; 123:1658–1666.
10.1001/archopht.123.12.1658 Crossref Medline, Google Scholar - 6.Grand MG, Burgess DB, Singerman LJ, Ramsey J. Choroidal osteoma: treatment of associated subretinal neovascular membranes. Retina. 1984; 4:84–89.
10.1097/00006982-198400420-00002 Crossref Medline, Google Scholar - 7.Maruko I, Iida T, Sugano Y, Subfoveal choroidal thickness after treatment of Vogt-Koyanagi-Harada disease. Retina. 2011; 31:510–517.
10.1097/IAE.0b013e3181eef053 Crossref Medline, Google Scholar - 8.Maruko I, Iida T, Sugano Y, Ojima A, Ogasawara M, Spaide RF. Subfoveal choroidal thickness after treatment of central serous chorioretinopathy. Ophthalmology. 2010; 117:1792–1799.
10.1016/j.ophtha.2010.01.023 Crossref Medline, Google Scholar

