Abstract
A 62-year-old female who was legally blind secondary to retinitis pigmentosa (RP) developed new positive visual phenomena (PVP) (“visual storms”) following implantation of the Argus II Retinal Prosthesis System (Second Sight Medical Products, Sylmar, CA). The potential mechanisms for the exacerbating PVP or hallucinatory release phenomena are proposed. Clinicians should be aware of these visual phenomena in patients with RP and the potential for worsening of or de novo development of PVP in patients considering the Argus II implant.
[Ophthalmic Surg Lasers Imaging Retina. 2017;48:1022–1025.]
- 1.da Cruz L, Dorn JD, Humayun MS, Five-year safety and performance results from the Argus II Retinal Prosthesis System clinical trial. Ophthalmology. 2016; 123(10):2248–2254.
10.1016/j.ophtha.2016.06.049 Crossref Medline, Google Scholar - 2.Ho AC, Humayun MS, Dorn JD, Long-term results from an epiretinal prosthesis to restore sight to the blind. Ophthalmology. 2015; 122(8):1547–1554.
10.1016/j.ophtha.2015.04.032 Crossref Medline, Google Scholar - 3.Olmos de Koo LC, Gregori NZ. The Argus II Retinal Prosthesis: A comprehensive review. Int Ophthalmol Clin. 2016; 56(4):39–46.
10.1097/IIO.0000000000000144 Crossref Medline, Google Scholar - 4.O'Hare F, Bentley SA, Wu Z, Guymer RH, Luu CD, Ayton LN. Charles Bonnet syndrome in advanced retinitis pigmentosa. Ophthalmology. 2015; 122(9):1951–1953.
10.1016/j.ophtha.2015.03.006 Crossref Medline, Google Scholar - 5.Menon GJ, Rahman I, Menon SJ, Dutton GN. Complex visual hallucinations in the visually impaired: The Charles Bonnet Syndrome. Surv Ophthalmol. 2003; 48(1):58–72.
10.1016/S0039-6257(02)00414-9 Crossref Medline, Google Scholar - 6.Santos-Bueso E, Serrador-Garcia M, Porta-Etessam J, [Charles Bonnet syndrome. A 45-case series]. Rev Neurol. 2015; 60(8):337–340. Medline, Google Scholar
- 7.Cox TM, ffytche DH. Negative outcome Charles Bonnet syndrome. Br J Ophthalmol. 2014; 98(9):1236–1239.
10.1136/bjophthalmol-2014-304920 Crossref Medline, Google Scholar
